I’ve got some awesome news for you – Cincinnati startups are making some serious waves lately! Can you believe it? They’re like the hidden gems of the startup world.

So, what’s the deal with these Cincinnati startups, you ask?

Well, let me break it down for you real quick:

  • These folks are innovating like crazy, and I’m not talking about your everyday, run-of-the-mill stuff. Nah, this is next-level innovation.
  • They’re all about collaboration, too. You know, the whole “teamwork makes the dream work” thing? They’ve got it in spades.

Now, in this article, we’re going to explore:

  1. The rising stars of Cincinnati startups (seriously, get ready to be impressed).
  2. The cutting-edge tech they’re developing (I can’t even wrap my head around some of it!).

So, my friends, get ready to be blown away by the extraordinary world of Cincinnati startups.


Gearsupply makes it more simpler and safer to buy and sell used concert equipment. Most significantly, however, they are fostering a neighbourhood around a dispersed concert production sector. Gearsupply concentrates on customer service, secure payment methods, and dependable shipping partners while charging the lowest fees in the sector. Gearsupply is excited to develop over the next three years as an early-stage startup with “basically no ceilings” by adding new team members, investing in technology, and increasing prospects for the business and its employees.

Enable Injections

A medical device firm called Enable Injections specialises in the development, production, and marketing of wearable injectable medicine delivery systems. The wearable can administer medications straight from conventional vials and, as part of the injection process, reconstitute powdered medications into liquids. The Enabling Smart enFuse can inject up to 20 ml of viscous liquid and features Bluetooth connectivity, which allows the user to monitor needle depth and infusion progress among other things.

Agar Corporation

The non-nuclear, adaptable, multi-phase flow metres invented by Agar Corporation are a market leader and are used to enhance oil well productivity and testing. For applications including heavy oil well testing, waste water treatment, automatic tank dewatering, desalters, and gas liquid foam management, Agar offers cutting-edge solutions. AGAR, which was founded in 2008, is a well-established business that values hiring University of Cincinnati alums; 23.7% of its staff are alumni. AGAR is a tiny media organisation with 200 employees and $21.0M in revenue that is situated in Cincinnati, Ohio.


Apache Airflow, the de facto standard for representing data flows as code, was created with the help of Astronomer. Each month, more than 4 million people download Airflow, which is used by hundreds of thousands of teams all over the world. Astronomer offers Astro, the cutting-edge data orchestration platform powered by Airflow, for data teams aiming to boost the accessibility of reliable data. Data engineers, data scientists, and data analysts may create, execute, and monitor pipelines-as-code with Astro. Astronomer, a global remote-first business with centres in Cincinnati, New York, San Francisco, and San Jose, was founded in 2018.


The CardioFlux Magnetocardiograph, their flagship device, is poised to be the most affordable response to the global dilemma of chest pain triage in the observation unit/emergency department. The technology is an imaging platform built on the idea of magnetocardiography (MCG), which has been studied for 45 years and allows for the passive measurement of the weak magnetic fields produced by the heart without the need of radiation or stress. They have created an intuitive backend for both the ER doctor and the cardiologist who would typically analyse stress test findings when thinking about percutaneous coronary intervention using their unique data science and visualisation techniques.

Coterie Insurance

The insurtech company Coterie Insurance makes it simple and affordable for anyone to purchase commercial insurance. It offers simple coverage, precise pricing, and a streamlined experience for any firm using an API-based methodology. You can obtain immediate coverage quotations and complete the underwriting procedure online as a business owner. With the click of a mouse, you may instantly obtain the coverage your company need. Because the platform allows them to digitise their business processes, agents and brokers can better serve independent contractors, small businesses in Cincinnati, and the gig economy.


 Mantium is a cloud platform for working with big language models and maintaining them at scale. It was founded in 2021 but is now entirely remote. It gives businesses the resources they need to quickly create and oversee large-scale, sophisticated, ethical AI applications. Teams may test, deploy, and monitor their AI systems using the low-code Mantium platform as an end-to-end solution. With Mantium, users can instantly share their prototypes with team members to get the input they need to improve their models. To enhance performance and get ready for a successful rollout, they can go over the logs and adjust the models.

CinCor Pharma

The goal of CinCor Pharma is to create the next wave of therapies for cardiovascular illnesses. It is now focused on creating baxdrostrat, a treatment for hypertension and other cardio-renal disorders, as a clinical-stage biopharmaceutical firm. As of September 30, 2022, CinCor reported having $522.5 million in cash, cash equivalents, and marketable securities. The net proceeds from the company’s initial public offering ($193.M), the follow-up selling of common stock and pre-funded warrants ($242.9M), and operating cash outflows ($52.4M) all contributed to the increase.


The online marketplace Pacaso allows users to buy or sell co-ownership properties. Users can browse and make reservations for single-family homes, hotels, condominiums, the development of property LLCs for homes, home furnishing management, repairs management, utility management, and property management. They have apps for iOS and Android devices.

Rhinegeist Brewery

Craft breweries and cideries can be found at Rhinegeist Brewery. In 2013, it was founded. Its name, which translates as “Ghost of the Rhine,” alludes to its location in Cincinnati, Ohio’s famed Over-the-Rhine Brewery District. Rhinegeist strives to produce beers that sing with taste and is housed inside the remains of a former brewery constructed before Prohibition. The Rhinegeist team is convinced that beer has the ability to unite brilliant people, spark amazing ideas, and create communities that love both craft beer and one another.

Luma Financial Technologies

The industry-leading, independent, multi-issuer platform for structured products and annuities is offered by Luma Financial Technologies. Since almost ten years ago, broker dealers and their advisers have been using the award-winning platform Luma to more effectively find, design, compare, and price structured products and annuities that suit their clients’ individual investment needs. The market for structured products and annuities is being driven forward by Luma’s advisor-centric design, renowned education and training capabilities, fully configurable deployment, and full product lifecycle support.


You can easily find high-returning properties on the Vairt marketplace; you don’t have to buy the entire property; you can invest in those properties by purchasing a small number of shares. Your shares will be liquid in your Vairt wallet, allowing you to simply sell them whenever you choose and get your money back. That’s really easy! You can invest in real estate easily thanks to Vairt in this way.


In order to aid organisations in team development, Cloverleaf automates duties related to individual and group coaching. By examining each employee’s personality and skills, they are able to get the most out of them and help them become better team members. The purpose of Cloverleaf is to equip business executives, team leaders, trainers, and consultants to recognise the individual value of every employee. The dashboard offers the information needed to increase the efficiency of conflict resolution and communication. The features of the service will also vary depending on the package you select. With team plans, you have access to 16 different types of personnel assessments, position recommendations, and connection mapping.


For women seeking the healthcare they deserve, HerMD is changing the rules of the game. HerMD specialists take the time to listen so that professionals and patients, together, can go through the best evidence-based solutions for patient health concerns. HerMD professionals offer in-person and virtual care for sexual health, menopause, gynaecology, medical aesthetics, and more. HerMD announced in March that it had raised $10 million to expand its female-focused healthcare model across the country. HerMD will be able to grow its telehealth network and add additional physical facilities in numerous states thanks to the money.


IP security software for 3D printers is offered by Physna LLC. Physical and DNA are referred to as Physna. According to their claims, every physical object has characteristic features similar to DNA in humans, and their software can recognise these properties in physical objects, establishing distinct database entries for each 3D product. The software stops the printing of prohibited items. It keeps rigorous quality control and can identify malfunctioning equipment.


With performance-contracted, carbon-free electrification-as-a-service to corporate, governmental, and institutional fleet customers across North America, Electrada is an up-and-coming leader in the transportation electrification industry. The fleet owner avoids the risks of electrification while reaping predictable savings and sustainability results for its stakeholders with Electrada’s unique, turnkey model that combines site energy engineering, supply optimization, and fleet analytics. The ecosystem of solutions offered by Electrada includes reputable partners in energy, microgrid, charging technologies, and fleet management who are committed to reducing transportation’s carbon footprint based on return on investment.


A multi-platform automated live and on-demand streaming platform is called StreamSpot. With the StreamSpot platform, broadcasters can use a variety of well-known encoders and apps, or, for the utmost in simplicity, they can use the StreamSpot ONE hardware device by StreamSpot, which makes use of the StreamSpot Sync® automation software and frees them from having to worry about setting up, starting, or stopping their broadcasts.

FAQ on Cincinnati startups

What’s the startup scene like in Cincinnati?

Well, Cincinnati has been growing rapidly as a hub for startups. The city offers a diverse ecosystem with support from accelerators, incubators, and venture capital firms. It’s an exciting place to be, with a vibrant community of entrepreneurs focused on various industries like healthcare, biotech, and consumer products. The cost of living is also relatively low, which makes it a great spot for new businesses.

How can I find Cincinnati-based startups?

You can find Cincinnati-based startups by checking out online resources like AngelList, Crunchbase, or local startup directories. You might also want to attend networking events, conferences, or meetups that are specific to the startup scene in Cincinnati. This way, you’ll be able to meet local entrepreneurs, investors, and other key players in the industry. Don’t forget to follow local news outlets and social media channels for updates on the latest startups.

Are there any success stories of Cincinnati startups?

Definitely! There have been several Cincinnati startups that have achieved great success. One example is Astronomer, a data engineering platform that raised over $20 million in funding. Another one is LISNR, a high-frequency data-over-audio technology company that’s been making waves. These are just a couple of examples, but there are many other startups that have been making their mark in the industry and showing that Cincinnati is a promising place for entrepreneurs.

What kind of support is available for startups in Cincinnati?

Cincinnati has a great support system for startups. You’ll find organizations like Cintrifuse, The Brandery, and HCDC that provide resources, mentorship, and funding opportunities for local startups. These organizations often host events and workshops to help entrepreneurs build their businesses and connect with like-minded people. In addition, you can also find coworking spaces and local universities that offer resources and support for new businesses.

Can I find funding for my startup in Cincinnati?

Absolutely! Cincinnati has a growing venture capital scene with firms like CincyTech, Allos Ventures, and Queen City Angels that actively invest in local startups. You can also explore angel investors, crowdfunding platforms, and government grants to help fund your business. Attending networking events and building relationships with key players in the community can be very helpful in securing funding as well.

Are there any startup incubators or accelerators in Cincinnati?

Yes, there are! Cincinnati has several incubators and accelerators like The Brandery, UpTech, and HCDC that are dedicated to helping startups grow and succeed. These programs often offer resources, mentorship, and even funding opportunities to participating startups. They can be a great way to accelerate your business and connect with valuable resources and networks in the industry.

How do I network with other entrepreneurs in Cincinnati?

Attending startup-focused events, conferences, and meetups is a great way to network with other entrepreneurs in Cincinnati. You can also join local online communities and social media groups where like-minded people share their experiences, advice, and opportunities. Networking is essential to building relationships and finding potential customers, investors, and partners, so be sure to get out there and make connections.

What are some challenges Cincinnati startups face?

While Cincinnati has a thriving startup scene, there are challenges that startups may face. These can include limited access to funding compared to larger startup hubs, difficulty in attracting top talent, and a smaller customer base compared to larger cities. However, Cincinnati’s growing support system, low cost of living, and dedicated entrepreneur community help offset these challenges and create a supportive environment for startups.

How can I hire talent for my Cincinnati startup?

You can find talent for your Cincinnati startup by attending local networking events, utilizing online job boards, and connecting with local universities and colleges. Engaging with the local community can help you tap into a pool of skilled individuals who are interested in joining the startup scene.

Additionally, leveraging social media platforms and reaching out to your network can help you find the right talent for your business. Don’t forget to highlight the unique opportunities and benefits of working at a startup to attract the best candidates.

Conclusion on these Cincinnati startups

Cincinnati is at the forefront of this new trend as more and more companies and venture capitalists start to seek outside of the crowded Silicon Valley tech market. Flyover cities have quickly emerged as desirable alternatives to the conventional tech centers on each coast. Over the past several years, the number of startup positions in Cincinnati has skyrocketed, and all signs point to this trend continuing in the years to come.

Despite having different names, most inhabitants refer to their city as Cincinnati. They include the City of Seven Hills, The ‘Nati, Queen City, Queen of the West, and Blue Chip City. There isn’t currently a catchy moniker for Cincinnati in the technology industry. We wouldn’t be shocked if it started going by the name “Silicon Queen,” though. Let’s wait and see what happens!

If you liked this article about Cincinnati startups, you should check out this article about Miami startups.

There are also similar articles discussing Phoenix startups, Nashville startups, Raleigh startups, and Chicago startups.

And let’s not forget about articles on Charlotte startups, Denver startups, Dallas startups, and Sacramento startups.


I'm the manager behind the Upcut Studio team. I've been involved in content marketing for quite a few years helping startups grow.